Search on: UNCOUPLING AGENTS 
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Descriptor English:   Uncoupling Agents 
Descriptor Spanish:   Desacopladores 
Descriptor Portuguese:   Desacopladores 
Synonyms English:   Agents, Uncoupling  
Tree Number:   D27.505.519.389.936
Definition English:   Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those IONOPHORES that disrupt electron transfer by short-circuiting the proton gradient across mitochondrial membranes. 
Indexing Annotation English:   enzyme inhib
See Related English:   Ionophores
 
History Note English:   72(69) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   14874 
Unique Identifier:   D014475 

Occurrence in VHL:
 

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